We study the role of WT1 in liver fibrosis and regeneration, exploring myofibroblast heterogeneity throughout the entire disease process Professor Tim Kendall Personal Chair of Liver Pathology, Senior Clinical Fellow in Pathology, Honorary Consultant Histopathologist Centre for Inflammation Research Contact details Website: Academic Profile Website: Human Genetics Unit Website: Pathology Work: +44 (0)131 242 7007 Email: Tim.Kendall@ed.ac.uk Research overviewThe WT1+ mesothelium contributes to the hepatic stellate cell population during development, and after fibrotic liver injury in the subcapsular region; loss of WT1 also influences liver parenchymal development. We aim to characterise the role of WT1 in hepatic stellate cells in fibrotic and non-fibrotic liver injury and regeneration.Research themeTranslational medicineBiographical profileUndertook a PhD In the Liver Research Group at the University of Southampton after starting specialist training in Histopathology, and then transferred to Edinburgh to complete clinical training in 2007. Started a Wellcome Trust Intermediate Clinical Fellowship in 2011, continuing clinical work as Honorary Consultant Histopathologist reporting liver and GI. Honours and awards2011 - Wellcome Trust Intermediate Clinical Fellowship2004 - Wellcome Trust Research Training Fellowship1997 - Wolfson Foundation StudentshipCollaboratorsLocalDr Luke Boulter (MRC Human Genetic Unit)Professor Nick Hastie (MRC Human Genetics Unit)Professor Stuart Forbes (MRC Centre for Regenerative Medicine)InternationalProfessor Andreas Schedl (Institute of Biology Valrose) Sources of FundingWellcome TrustMore information on funding at Tim Kendall's Research Explorer profile. This article was published on 2024-09-10