Damage and Repair

The Damage and Repair research theme investigates how tissues respond to inflammatory injury and the long-term effects of chronic inflammation.

Researchers study the cellular and molecular mechanisms behind tissue damage, repair, and regeneration across organs such as the liver, kidney, lung, and skin.

A key focus is understanding how chronic inflammation contributes to diseases like cancer, including the roles of ageing cells, impaired repair, and cell interactions that lead to scarring. Using advanced single-cell technologies, our research helps reveal promising targets for future therapies.

Key areas of focus

  • Long-term (chronic) inflammation
  • Consequences of inflammation
  • Tissue repair and regeneration
  • Damage or injury to tissue
  • Application to liver, kidney, lung, skin and cancer
  • Single-cell approaches

Theme Leads: Prakash Ramachandran and Sonja Vermeren

Immunofluorescence image of a diabetic foot ulcer.
Immunofluorescence image of a diabetic foot ulcer (credit: Dr Jenna Cash)

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