Professor Tim Kendall

We aim to understand how chronic liver disease and liver cancer develop and respond to treatment.

To understand chronic liver disease and liver cancer better, we study large real-world datasets from the clinic and histology stains of diseased tissue seen under a microscope. We have a particular focus on steatotic liver disease, which we can replicate in a lab setting and on the computer. These computational models allow us to make predictions from routine histological stains, primarily in liver disease but also to diseases beyond the liver.

Professor Tim Kendall

Personal Chair of Liver Pathology, Senior Clinical Fellow in Pathology, Honorary Consultant Histopathologist

  • Centre for Inflammation Research

Contact details

Group members

Aino Kortelainen, Clinical Research Fellow in Digital Pathology

Frank Wu, PhD Student,

Research overview

The WT1+ mesothelium contributes to the hepatic stellate cell population during development, and after fibrotic liver injury in the subcapsular region; loss of WT1 also influences liver parenchymal development. We aim to characterise the role of WT1 in hepatic stellate cells in fibrotic and non-fibrotic liver injury and regeneration.

Research theme

Translational medicine

Biographical profile

Undertook a PhD In the Liver Research Group at the University of Southampton after starting specialist training in Histopathology, and then transferred to Edinburgh to complete clinical training in 2007. Started a Wellcome Trust Intermediate Clinical Fellowship in 2011, continuing clinical work as Honorary Consultant Histopathologist reporting liver and GI. 

Honours and awards

  • 2011 - Wellcome Trust Intermediate Clinical Fellowship
  • 2004 - Wellcome Trust Research Training Fellowship
  • 1997 - Wolfson Foundation Studentship

Collaborators

Local

Dr Luke Boulter (MRC Human Genetic Unit)

Professor Nick Hastie (MRC Human Genetics Unit)

Professor Stuart Forbes (MRC Centre for Regenerative Medicine)

International

Professor Andreas Schedl (Institute of Biology Valrose)

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